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Arthrosamid

A cutting edge injectable implant technology for the treatment of all severities of knee arthritis.
A single injection has been clinically proven to give years of pain relief, restoring function and increasing mobility.

AT A GLANCE

TREATS

Mild to severe knee osteoarthritis

Anaesthesia

 Local anesthetic

Duration

30 minutes

Recovery

48h of reduced activity 

LONDON BRIDGE - Regenerative Clinic

ARTHROSAMID​ Injections

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WHAT IS KNEE OSTEOARTHRITIS?

Knee osteoarthritis, a chronic condition affecting the knee bones and joints, progressively deteriorates over time, leading to discomfort and reduced mobility. Primarily affecting the knee joint, it erodes the cushioning cartilage, resulting in bone friction and stiffness. Consequently, the joint becomes swollen and painful.
The exact cause of knee osteoarthritis remains elusive, and as of now, no permanent remedy exists. Current treatments primarily focus on symptom management and include:
Exercise
Weight loss
Pain relief medication
Viscosupplement injections
Braces
Physical therapy
However, when these interventions prove ineffective, patients often resort to total knee replacement surgery as a last resort. Yet, a promising shift is on the horizon.

How Does Arthrosamid Work to Treat Knee Pain?

The knee joint comprises a thin membrane known as the synovium, which houses small synovial cells responsible for producing lubricant fluid, allowing the joints to glide and acting as a shock absorber. In cases of arthritis, this synovium often becomes inflamed and irritated, leading to synovitis. Arthrosamid Hydrogel injection aids in alleviating this inflammation by being absorbed by the synovial cells, which then become more dispersed, diminishing the transmission of inflammatory signals. Additionally, the hydrogel serves as a cushion within the knee joint. It typically takes approximately 6-8 weeks post-injection for Arthrosamid to integrate with the synovial cells and begin reducing knee joint pain, swelling, and increasing function.

WHAT EXACTLY IS ARTHROSAMID®?

Arthrosamid® stands out as a new long lasting approach to treating knee osteoarthritis, providing patients with a compelling long ter alternative to existing therapies such as steroids. Utilizing cutting-edge non-biodegradable hydrogel technology, Arthrosamid® comprises 2.5% cross-linked polyacrylamide and 97.5% water. Upon injection into the knee, Arthrosamid® effectively cushions the joint, alleviating pain and offering safe, long-lasting relief, all achieved with just a single injection.

How Does Arthrosamid Work to Treat Knee Pain?

The knee joint comprises a thin membrane known as the synovium, which houses small synovial cells responsible for producing lubricant fluid, allowing the joints to glide and acting as a shock absorber. In cases of arthritis, this synovium often becomes inflamed and irritated, leading to synovitis. Arthrosamid Hydrogel injection aids in alleviating this inflammation by being absorbed by the synovial cells, which then become more dispersed, diminishing the transmission of inflammatory signals. Additionally, the hydrogel serves as a cushion within the knee joint. It typically takes approximately 6-8 weeks post-injection for Arthrosamid to integrate with the synovial cells and begin reducing knee joint pain, swelling, and increasing function.

Discover More About Sharron Davies' 3-month Post Treatment

POST-TREATMENT JOURNEY

Safe and sustained pain relief for knee osteoarthritis with a single injection

Arthrosamid® is a non-biodegradable hydrogel which helps to support and cushion the joint and alleviate pain.

Arthrosamid® is injected into the intra-articular space as a minimally invasive, out-patient procedure in our clinic

Eliminate the need for more aggressive treatments, such as surgery

long-lasting pain relief for knee osteoarthritis through a single injection while ensuring safety.

Arthrosamid injection: an innovative new advanced treatment for knee arthritis!

Knee osteoarthritis is a prevalent condition seen in clinics. Typically, treatment for knee osteoarthritis begins with conservative approaches and the use of anti-inflammatory drugs. However, when conventional methods prove ineffective, injection therapy emerges as a crucial component in management. Arthrosamid presents a promising new treatment avenue for all severities of knee arthritis. Book a free initial assessment today at London Bridge Regenerative Clinic.

ARTHROSAMID® TREATMENT OVERVIEW

Arthrosamid presents an encouraging new therapeutic choice for knee arthritis, with its roots tracing back to Denmark and its availability in the UK for a few years now, research results are looking promising for the injections long term efficacy.

WHAT EXACTLY IS ARTHROSAMID®?

Arthrosamid® stands out as a new long lasting approach to treating knee osteoarthritis, providing patients with a compelling long term alternative to existing therapies such as steroids. Utilising cutting-edge non-biodegradable hydrogel technology, Arthrosamid® comprises 2.5% cross-linked polyacrylamide and 97.5% water. Upon injection into the knee, Arthrosamid® effectively cushions the joint, alleviating pain and offering safe, long-lasting relief, all achieved with just a single injection.

What Evidence Supports the Use of Arthrosamid Injections in Knee Arthritis?

In recent years, several small-scale studies have examined the efficacy and safety of Arthrosamid for treating knee arthritis. These studies have shown notable improvements in knee pain and swelling post-injection, along with enhancements in scores assessing the severity of knee arthritis and its impact on quality of life. More recently, larger and more robust studies have been conducted to evaluate the effects of Arthrosamid. For instance, a multi-center, double-blinded, randomized controlled trial compared the effects of Hydrogel injections to Hyaluronic acid, revealing positive outcomes in both patient groups for up to one year . Bliddal, H., et al. (2022). One-year performance of polyacrylamide hydrogel vs. hyaluronic acid in age, BMI, and Kellgren-Lawrence subgroups: A subgroup analysis of a randomised study. Osteoarthritis and Cartilage Vol.30, Supplement 1, S373-S374.

The most recent data on Arthrosamid injection suggests its effectiveness persists in many patients even three years after the procedure. This prospective study, involving patients with an average age of approximately 70 years, found that the hydrogel forms a stable, long-lasting layer covering the joint surface . 

Arthrosamid has demonstrated both efficacy and safety in relieving symptomatic knee osteoarthritis, making it a generally favorable treatment option for numerous patients. Nonetheless, it’s recommended to consult with one of our injection practitioners who can thoroughly explain the risks and benefits of the procedure, as well as explore alternative therapies that may be beneficial.

 

Administering the Arthrosamid hydrogel involves directly injecting it into the knee joint under ultrasound guidance, a crucial step for ensuring maximum precision and accuracy in delivery. Research indicates that unguided knee injections have an accuracy rate of approximately 80%.

  • Existing knee replacement or prosthesis.
  • History of knee keyhole surgery (arthroscopy) within the past 6 months.
  • Certain conditions affecting the joints, such as haemophilia, autoimmune diseases, or inflammatory arthritis.
  • Recent hyaluronic acid injection into the knee; it’s advised to wait until the previous injection is absorbed, with the duration varying according to the specific hyaluronic acid preparation used.
  • Certain medications and blood disorders. This will be fully discussed during your initial consultation to ascertain the suitability of the treatment and answer any questions you may have.

Arthrosamid is administered with ultrasound guidance to enhance the precision and safety of the injection process. Without ultrasound guidance, the accuracy of knee injections is only around 80%, as shown by studies. Therefore, utilizing ultrasound ensures that Arthrosamid is injected precisely into the knee joint, maximizing its effectiveness and safety for the patient.

The duration of Arthrosamid’s effect is promising, with recent studies showing that its benefits were maintained for up to 3 years of follow-up. Contura, the manufacturer of Arthrosamid, is actively monitoring the long-term response to this hydrogel treatment. Since the Arthrosamid hydrogel cannot be degraded by the body, it offers the potential for long-term pain relief, providing patients with sustained benefits over time.

Patients typically begin to notice pain relief within a few weeks after receiving the injection. It is common to experience temporary discomfort in the knee for the first few days after the procedure. Pain relief from the injection can usually start to be felt at around 4 weeks, but the full benefits may take up to 4 months to become apparent.

At London Bridge Regeneration clinic we provide various payment options meaning you can spread the cost and enjoy a confident outlook at a price you can afford this can also include interest free options.
Please book a complimentary initial consultation to discuss, your tailored and best options your but typically prices start as shown below
Procedure

Practitioner

Practitioner fee

Arthrosamid

Jon Handley-Collins

£2400 (one knee) £4600 (both knees)

Arthrosamid Injection

How Does Arthrosamid Work to Treat Knee Pain?

The knee joint comprises a thin membrane known as the synovium, which houses small synovial cells responsible for producing lubricant fluid, allowing the joints to glide and acting as a shock absorber. In cases of arthritis, this synovium often becomes inflamed and irritated, leading to synovitis. Arthrosamid Hydrogel injection aids in alleviating this inflammation by being absorbed by the synovial cells, which then become more dispersed, diminishing the transmission of inflammatory signals. Additionally, the hydrogel serves as a cushion within the knee joint. It typically takes approximately 6-8 weeks post-injection for Arthrosamid to integrate with the synovial cells and begin reducing knee joint pain, swelling, and increasing function.

The Procedure:

Before the injection, you’ll receive a single dose of antibiotics to mitigate the risk of infection. These will be sent to your home and should be taken 2 hours before your injection.  A pre-procedure ultrasound scan of the knee will be conducted to pinpoint the optimal site for the injection and assess any excess fluid in the joint. Following this, the skin will be cleaned and prepared using sterile techniques. A small amount of local anaesthetic will be administered to numb the area. Subsequently, under continuous ultrasound guidance, the Arthrosamid hydrogel will be accurately injected into the knee joint. If there is any excess fluid present, it will be aspirated before the Arthrosamid injection.

It is important to follow your clinician post-procedure instructions carefully and attend follow the knee rehabilitation programme.

ESSKA 2022 - Introducing Arthrosamid

a new class of injectable therapy to treat knee OA​

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YOUR SIMPLE 4 STEP JOURNEY

Step 1. Free Intial consultation

London Bridge Regenerative clinic gives every patient a free consultation with one of our injecting practitioners.  This includes a free ultrasound scan if required.

There is no obligation to proceed to treatment. The consultation is an opportunity to discuss your issue in detail and the benefits and risks of the procedure.

STEP 2. PHYSICAL EXAM AND ULTRASOUND

We will perform palpation and orthopaedic tests to help confirm your diagnosis.  If required we may also perform a diagnostic ultrasound scan to assist in visualising the issue.  We may also refer you for an X-ray or MRI, depending on the examination findings.  

We will allow time to explain the procedure and answer any questions you may have.  We make sure you understand the advantages and risks with the procedure before going ahead

 

STEP 3. Injection procedure

You’ll be given individual pre-injection advice to reduce your chance of bleeding or infection and support your recovery and aid healing

It’s important to let your practitioner know if you’re on any prescription or over-the-counter medications. You may be asked to stop taking aspirin or anti-inflammatory tablets, which can increase the risk of bruising. It’s also important to stop smoking cigarettes and e-cigarettes before and after the procedure because they can disrupt the healing process.

Local aesthetic is normally needed as well is an antibiotic which must be taken 2 hours before the procedure 

STEP 4: RECOVERY AND FOLLOW UP

Following the procedure, most individuals can return home and resume their normal activities. Our clinical team will be available to offer water and provide guidance on post-injection care.

For the next 48 hours, it’s advisable to refrain from strenuous activities and alcohol consumption. Don’t be alarmed if you don’t notice immediate effects; it typically takes around 4 weeks for the injection to take effect, with the full results becoming evident over the course of 4 months.

A follow-up appointment or phone consultation will be scheduled for 4 months after the course of treatment to review the progress. 

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HAVE A QUESTION?

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MEET THE TEAM

Gary Edwards

Doctor of Chiropractic and Injection therapy

Jon Handley-Collins

Doctor of Chiropractic and Injection therapy

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To book you free consultation,  please complete the form below.  One of our practitioners will contact you to discuss your condition and schedule your appointment.  

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